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AKT2-UPF1 Gene Fusion FISH Probe

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Catalog: GFFP-AKT2/UPF1-00591
Classification: Gene Fusion FISH Probes
Description: The AKT2-UPF1 Gene Fusion FISH Probecan detect the fusion of AKT2 and UPF1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: AKT2-UPF1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 AKT Serine/threonine Kinase 2
Gene Summary 1 This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 19
Locus 1 19q13.2
Coordinates 1 This gene maps to 40736223-40791302 in GRCh37 coordinates.
Gene Name 2 UPF1, RNA Helicase And ATPase
Gene Summary 2 This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Chromosome 2 Chromosome19
Locus 2 19p13.11
Coordinates 2 This gene maps to 18942743-18979039 in GRCh37 coordinates.
Associated Diseases Brain Lower Grade Glioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-AKT2/UPF1-00591-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-AKT2/UPF1-00591-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-AKT2/UPF1-00591-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-AKT2/UPF1-00591-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-AKT2/UPF1-00591-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-AKT2/UPF1-00591-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-AKT2/UPF1-00591-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-AKT2/UPF1-00591-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-AKT2/UPF1-00591-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-AKT2/UPF1-00591-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-AKT2/UPF1-00591-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-AKT2/UPF1-00591-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-AKT2/UPF1-00591-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-AKT2/UPF1-00591-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-AKT2/UPF1-00591-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-AKT2/UPF1-00591-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-AKT2/UPF1-00591-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-AKT2/UPF1-00591-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-AKT2/UPF1-00591-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-AKT2/UPF1-00591-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-AKT2/UPF1-00591-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-AKT2/UPF1-00591-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-AKT2/UPF1-00591-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-AKT2/UPF1-00591-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-AKT2/UPF1-00591-AQAQ 467nm;467nm 418nm;418nm

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