AKT2-ELK3 Gene Fusion FISH Probe
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Catalog: |
GFFP-AKT2/ELK3-00592 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The AKT2-ELK3 Gene Fusion FISH Probecan detect the fusion of AKT2 and ELK3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
AKT2-ELK3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
AKT Serine/threonine Kinase 2 |
Gene Summary 1 |
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19q13.2 |
Coordinates 1 |
This gene maps to 40736223-40791302 in GRCh37 coordinates. |
Gene Name 2 |
ELK3, ETS Transcription Factor |
Gene Summary 2 |
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
Chromosome 2 |
Chromosome12 |
Locus 2 |
12q23.1 |
Coordinates 2 |
This gene maps to 96588206-96661606 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-AKT2/ELK3-00592-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-AKT2/ELK3-00592-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-AKT2/ELK3-00592-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-AKT2/ELK3-00592-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-AKT2/ELK3-00592-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-AKT2/ELK3-00592-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-AKT2/ELK3-00592-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-AKT2/ELK3-00592-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-AKT2/ELK3-00592-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-AKT2/ELK3-00592-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-AKT2/ELK3-00592-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-AKT2/ELK3-00592-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-AKT2/ELK3-00592-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-AKT2/ELK3-00592-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-AKT2/ELK3-00592-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-AKT2/ELK3-00592-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-AKT2/ELK3-00592-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-AKT2/ELK3-00592-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-AKT2/ELK3-00592-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-AKT2/ELK3-00592-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-AKT2/ELK3-00592-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-AKT2/ELK3-00592-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-AKT2/ELK3-00592-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-AKT2/ELK3-00592-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-AKT2/ELK3-00592-AQAQ |
467nm;467nm |
418nm;418nm |
|
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