AKAP13-CHD2 Gene Fusion FISH Probe
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Catalog: |
GFFP-AKAP13/CHD2-00619 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The AKAP13-CHD2 Gene Fusion FISH Probecan detect the fusion of AKAP13 and CHD2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
AKAP13-CHD2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Chromodomain Helicase DNA Binding Protein 2 |
Gene Summary 1 |
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 15 |
Locus 1 |
15q26.1 |
Coordinates 1 |
This gene maps to 93443550-93571237 in GRCh37 coordinates. |
Gene Name 2 |
A-kinase Anchoring Protein 13 |
Gene Summary 2 |
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012] |
Chromosome 2 |
Chromosome15 |
Locus 2 |
15q25.3 |
Coordinates 2 |
This gene maps to 85923870-86292586 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-AKAP13/CHD2-00619-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-AKAP13/CHD2-00619-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-AKAP13/CHD2-00619-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-AKAP13/CHD2-00619-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-AKAP13/CHD2-00619-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-AKAP13/CHD2-00619-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-AKAP13/CHD2-00619-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-AKAP13/CHD2-00619-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-AKAP13/CHD2-00619-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-AKAP13/CHD2-00619-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-AKAP13/CHD2-00619-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-AKAP13/CHD2-00619-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-AKAP13/CHD2-00619-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-AKAP13/CHD2-00619-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-AKAP13/CHD2-00619-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-AKAP13/CHD2-00619-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-AKAP13/CHD2-00619-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-AKAP13/CHD2-00619-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-AKAP13/CHD2-00619-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-AKAP13/CHD2-00619-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-AKAP13/CHD2-00619-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-AKAP13/CHD2-00619-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-AKAP13/CHD2-00619-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-AKAP13/CHD2-00619-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-AKAP13/CHD2-00619-AQAQ |
467nm;467nm |
418nm;418nm |
|
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