AK2-MKL1 Gene Fusion FISH Probe
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| Catalog: |
GFFP-AK2/MKL1-00307 |
| Classification: |
Gene Fusion FISH Probes |
| Description: |
The AK2-MKL1 Gene Fusion FISH Probecan detect the fusion of AK2 and MKL1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Category: |
Gene Fusion FISH Probes |
| Application: |
AK2-MKL1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name 1 |
Adenylate Kinase 2 |
| Gene Summary 1 |
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.[provided by RefSeq, Nov 2010] |
| Chromosome 1 |
Chromosome 1 |
| Locus 1 |
1p35.1 |
| Coordinates 1 |
This gene maps to 33473540-33502512 in GRCh37 coordinates. |
| Gene Name 2 |
Megakaryoblastic Leukemia (translocation) 1 |
| Gene Summary 2 |
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| Chromosome 2 |
Chromosome22 |
| Locus 2 |
22q13.1-q13.2 |
| Coordinates 2 |
This gene maps to 40806291-41032690 in GRCh37 coordinates. |
| Associated Diseases |
Stomach Adenocarcinoma |
| Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
RE; RE
|
GFFP-AK2/MKL1-00307-RERE |
599nm;599nm |
580nm;580nm |
|
| 2 |
RE; OR
|
GFFP-AK2/MKL1-00307-REOR |
599nm;573nm |
580nm;548nm |
|
| 3 |
RE; GO
|
GFFP-AK2/MKL1-00307-REGO |
599nm;551nm |
580nm;525nm |
|
| 4 |
RE; GR
|
GFFP-AK2/MKL1-00307-REGR |
599nm;515nm |
580nm;491nm |
|
| 5 |
RE; AQ
|
GFFP-AK2/MKL1-00307-REAQ |
599nm;467nm |
580nm;418nm |
|
| 6 |
OR; RE
|
GFFP-AK2/MKL1-00307-ORRE |
573nm;599nm |
548nm;580nm |
|
| 7 |
OR; OR
|
GFFP-AK2/MKL1-00307-OROR |
573nm;573nm |
548nm;548nm |
|
| 8 |
OR; GO
|
GFFP-AK2/MKL1-00307-ORGO |
573nm;551nm |
548nm;525nm |
|
| 9 |
OR; GR
|
GFFP-AK2/MKL1-00307-ORGR |
573nm;515nm |
548nm;491nm |
|
| 10 |
OR; AQ
|
GFFP-AK2/MKL1-00307-ORAQ |
573nm;467nm |
548nm;418nm |
|
| 11 |
GO; RE
|
GFFP-AK2/MKL1-00307-GORE |
551nm;599nm |
525nm;580nm |
|
| 12 |
GO; OR
|
GFFP-AK2/MKL1-00307-GOOR |
551nm;573nm |
525nm;548nm |
|
| 13 |
GO; GO
|
GFFP-AK2/MKL1-00307-GOGO |
551nm;551nm |
525nm;525nm |
|
| 14 |
GO; GR
|
GFFP-AK2/MKL1-00307-GOGR |
551nm;515nm |
525nm;491nm |
|
| 15 |
GO; AQ
|
GFFP-AK2/MKL1-00307-GOAQ |
551nm;467nm |
525nm;418nm |
|
| 16 |
GR; RE
|
GFFP-AK2/MKL1-00307-GRRE |
515nm;599nm |
491nm;580nm |
|
| 17 |
GR; OR
|
GFFP-AK2/MKL1-00307-GROR |
515nm;573nm |
491nm;548nm |
|
| 18 |
GR; GO
|
GFFP-AK2/MKL1-00307-GRGO |
515nm;551nm |
491nm;525nm |
|
| 19 |
GR; GR
|
GFFP-AK2/MKL1-00307-GRGR |
515nm;515nm |
491nm;491nm |
|
| 20 |
GR; AQ
|
GFFP-AK2/MKL1-00307-GRAQ |
515nm;467nm |
491nm;418nm |
|
| 21 |
AQ; RE
|
GFFP-AK2/MKL1-00307-AQRE |
467nm;599nm |
418nm;580nm |
|
| 22 |
AQ; OR
|
GFFP-AK2/MKL1-00307-AQOR |
467nm;573nm |
418nm;548nm |
|
| 23 |
AQ; GO
|
GFFP-AK2/MKL1-00307-AQGO |
467nm;551nm |
418nm;525nm |
|
| 24 |
AQ; GR
|
GFFP-AK2/MKL1-00307-AQGR |
467nm;515nm |
418nm;491nm |
|
| 25 |
AQ; AQ
|
GFFP-AK2/MKL1-00307-AQAQ |
467nm;467nm |
418nm;418nm |
|
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