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AFF1-C4ORF36 Gene Fusion FISH Probe

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Catalog: GFFP-AFF1/C4ORF36-00374
Classification: Gene Fusion FISH Probes
Description: The AFF1-C4ORF36 Gene Fusion FISH Probecan detect the fusion of AFF1 and C4ORF36 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: AFF1-C4ORF36 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 AF4/FMR2 Family Member 1
Gene Summary 1 This gene encodes a member of the AF4/ lymphoid nuclear protein related to the Fragile X E syndrome (FRAXE) family of proteins, which have been implicated in human childhood lymphoblastic leukemia, fragile chromosome X intellectual disability, and ataxia. It is the prevalent mixed-lineage leukemia fusion gene associated with spontaneous acute lymphoblastic leukemia. Members of this family have three conserved domains: an N-terminal homology domain, an AF4/ lymphoid nuclear protein domain, and a C-terminal homology domain. The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling functions. Through RNA interference screens, this gene has been shown to promote the expression of CD133, a plasma membrane glycoprotein required for leukemia cell survival. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
Chromosome 1 Chromosome 4
Locus 1 4q21.3-q22.1
Coordinates 1 This gene maps to 87856153-88062206 in GRCh37 coordinates.
Gene Name 2 Chromosome 4 Open Reading Frame 36
Gene Summary 2 The Chromosome 4 Open Reading Frame 36 (C4orf36) gene is located on chr4 :87797357-87813575 at 4q21.3.
Chromosome 2 Chromosome4
Locus 2 4q21.3
Coordinates 2 This gene maps to 87797357-87813575 in GRCh37 coordinates.
Associated Diseases Sarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-AFF1/C4ORF36-00374-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-AFF1/C4ORF36-00374-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-AFF1/C4ORF36-00374-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-AFF1/C4ORF36-00374-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-AFF1/C4ORF36-00374-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-AFF1/C4ORF36-00374-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-AFF1/C4ORF36-00374-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-AFF1/C4ORF36-00374-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-AFF1/C4ORF36-00374-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-AFF1/C4ORF36-00374-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-AFF1/C4ORF36-00374-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-AFF1/C4ORF36-00374-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-AFF1/C4ORF36-00374-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-AFF1/C4ORF36-00374-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-AFF1/C4ORF36-00374-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-AFF1/C4ORF36-00374-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-AFF1/C4ORF36-00374-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-AFF1/C4ORF36-00374-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-AFF1/C4ORF36-00374-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-AFF1/C4ORF36-00374-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-AFF1/C4ORF36-00374-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-AFF1/C4ORF36-00374-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-AFF1/C4ORF36-00374-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-AFF1/C4ORF36-00374-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-AFF1/C4ORF36-00374-AQAQ 467nm;467nm 418nm;418nm

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