ADAMTS17-PCDHA8 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-ADAMTS17/PCDHA8-00059 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ADAMTS17-PCDHA8 Gene Fusion FISH Probe can detect the fusion of ADAMTS17 and PCDHA8 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ADAMTS17-PCDHA8 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Protocadherin Alpha 8 |
Gene Summary 1 |
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 5 |
Locus 1 |
5q31.3 |
Coordinates 1 |
This gene maps to 140220906-140391929 in GRCh37 coordinates. |
Gene Name 2 |
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 17 |
Gene Summary 2 |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may promote breast cancer cell growth and survival. Mutations in this gene are associated with a Weill-Marchesani-like syndrome, which is characterized by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. [provided by RefSeq, May 2016] |
Chromosome 2 |
Chromosome15 |
Locus 2 |
15q26.3 |
Coordinates 2 |
This gene maps to 100511642-100882183 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ADAMTS17/PCDHA8-00059-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ADAMTS17/PCDHA8-00059-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ADAMTS17/PCDHA8-00059-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ADAMTS17/PCDHA8-00059-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ADAMTS17/PCDHA8-00059-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ADAMTS17/PCDHA8-00059-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ADAMTS17/PCDHA8-00059-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ADAMTS17/PCDHA8-00059-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ADAMTS17/PCDHA8-00059-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ADAMTS17/PCDHA8-00059-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ADAMTS17/PCDHA8-00059-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ADAMTS17/PCDHA8-00059-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ADAMTS17/PCDHA8-00059-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ADAMTS17/PCDHA8-00059-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ADAMTS17/PCDHA8-00059-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ADAMTS17/PCDHA8-00059-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ADAMTS17/PCDHA8-00059-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ADAMTS17/PCDHA8-00059-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ADAMTS17/PCDHA8-00059-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ADAMTS17/PCDHA8-00059-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ADAMTS17/PCDHA8-00059-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ADAMTS17/PCDHA8-00059-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ADAMTS17/PCDHA8-00059-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ADAMTS17/PCDHA8-00059-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ADAMTS17/PCDHA8-00059-AQAQ |
467nm;467nm |
418nm;418nm |
|
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