ACTN4-MGST2 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-ACTN4/MGST2-00069 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ACTN4-MGST2 Gene Fusion FISH Probe can detect the fusion of ACTN4 and MGST2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ACTN4-MGST2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Actinin Alpha 4 |
Gene Summary 1 |
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19q13.2 |
Coordinates 1 |
This gene maps to 39138266-39221171 in GRCh37 coordinates. |
Gene Name 2 |
Microsomal Glutathione S-transferase 2 |
Gene Summary 2 |
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011] |
Chromosome 2 |
Chromosome4 |
Locus 2 |
4q31.1 |
Coordinates 2 |
This gene maps to 140586921-140661899 in GRCh37 coordinates. |
Associated Diseases |
Prostate Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ACTN4/MGST2-00069-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ACTN4/MGST2-00069-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ACTN4/MGST2-00069-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ACTN4/MGST2-00069-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ACTN4/MGST2-00069-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ACTN4/MGST2-00069-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ACTN4/MGST2-00069-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ACTN4/MGST2-00069-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ACTN4/MGST2-00069-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ACTN4/MGST2-00069-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ACTN4/MGST2-00069-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ACTN4/MGST2-00069-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ACTN4/MGST2-00069-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ACTN4/MGST2-00069-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ACTN4/MGST2-00069-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ACTN4/MGST2-00069-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ACTN4/MGST2-00069-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ACTN4/MGST2-00069-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ACTN4/MGST2-00069-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ACTN4/MGST2-00069-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ACTN4/MGST2-00069-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ACTN4/MGST2-00069-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ACTN4/MGST2-00069-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ACTN4/MGST2-00069-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ACTN4/MGST2-00069-AQAQ |
467nm;467nm |
418nm;418nm |
|
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