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ACTL6A-ALG3 Gene Fusion FISH Probe

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Catalog: GFFP-ACTL6A/ALG3-13805
Classification: Gene Fusion FISH Probes
Description: The ACTL6A-ALG3 Gene Fusion FISH Probe can detect the fusion of ACTL6A and ALG3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ACTL6A-ALG3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Actin Like 6A
Gene Summary 1 This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 3
Locus 1 3q26.33
Coordinates 1 This gene maps to 179280707-179306193 in GRCh37 coordinates.
Gene Name 2 ALG3, Alpha-1,3- Mannosyltransferase
Gene Summary 2 This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Chromosome 2 Chromosome3
Locus 2 3q27.1
Coordinates 2 This gene maps to 183960116-183967313 in GRCh37 coordinates.
Associated Diseases Head And Neck Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ACTL6A/ALG3-13805-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ACTL6A/ALG3-13805-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ACTL6A/ALG3-13805-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ACTL6A/ALG3-13805-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ACTL6A/ALG3-13805-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ACTL6A/ALG3-13805-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ACTL6A/ALG3-13805-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ACTL6A/ALG3-13805-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ACTL6A/ALG3-13805-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ACTL6A/ALG3-13805-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ACTL6A/ALG3-13805-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ACTL6A/ALG3-13805-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ACTL6A/ALG3-13805-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ACTL6A/ALG3-13805-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ACTL6A/ALG3-13805-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ACTL6A/ALG3-13805-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ACTL6A/ALG3-13805-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ACTL6A/ALG3-13805-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ACTL6A/ALG3-13805-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ACTL6A/ALG3-13805-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ACTL6A/ALG3-13805-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ACTL6A/ALG3-13805-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ACTL6A/ALG3-13805-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ACTL6A/ALG3-13805-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ACTL6A/ALG3-13805-AQAQ 467nm;467nm 418nm;418nm

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