ACSL3-PHGDH Gene Fusion FISH Probe
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Catalog: |
GFFP-ACSL3/PHGDH-00136 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ACSL3-PHGDH Gene Fusion FISH Probe can detect the fusion of ACSL3 and PHGDH genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ACSL3-PHGDH Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Acyl-CoA Synthetase Long Chain Family Member 3 |
Gene Summary 1 |
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 2 |
Locus 1 |
2q36.1 |
Coordinates 1 |
This gene maps to 223725731-223808119 in GRCh37 coordinates. |
Gene Name 2 |
Phosphoglycerate Dehydrogenase |
Gene Summary 2 |
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1p12 |
Coordinates 2 |
This gene maps to 120254418-120286849 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ACSL3/PHGDH-00136-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ACSL3/PHGDH-00136-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ACSL3/PHGDH-00136-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ACSL3/PHGDH-00136-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ACSL3/PHGDH-00136-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ACSL3/PHGDH-00136-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ACSL3/PHGDH-00136-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ACSL3/PHGDH-00136-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ACSL3/PHGDH-00136-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ACSL3/PHGDH-00136-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ACSL3/PHGDH-00136-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ACSL3/PHGDH-00136-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ACSL3/PHGDH-00136-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ACSL3/PHGDH-00136-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ACSL3/PHGDH-00136-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ACSL3/PHGDH-00136-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ACSL3/PHGDH-00136-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ACSL3/PHGDH-00136-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ACSL3/PHGDH-00136-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ACSL3/PHGDH-00136-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ACSL3/PHGDH-00136-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ACSL3/PHGDH-00136-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ACSL3/PHGDH-00136-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ACSL3/PHGDH-00136-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ACSL3/PHGDH-00136-AQAQ |
467nm;467nm |
418nm;418nm |
|
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