ACACA-HTRA4 Gene Fusion FISH Probe
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Catalog: |
GFFP-ACACA/HTRA4-00157 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ACACA-HTRA4 Gene Fusion FISH Probe can detect the fusion of ACACA and HTRA4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ACACA-HTRA4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Acetyl-CoA Carboxylase Alpha |
Gene Summary 1 |
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q12 |
Coordinates 1 |
This gene maps to 35441926-35766902 in GRCh37 coordinates. |
Gene Name 2 |
HtrA Serine Peptidase 4 |
Gene Summary 2 |
This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008] |
Chromosome 2 |
Chromosome8 |
Locus 2 |
8p11.22 |
Coordinates 2 |
This gene maps to 38831667-38846181 in GRCh37 coordinates. |
Associated Diseases |
Bladder Urothelial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ACACA/HTRA4-00157-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ACACA/HTRA4-00157-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ACACA/HTRA4-00157-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ACACA/HTRA4-00157-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ACACA/HTRA4-00157-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ACACA/HTRA4-00157-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ACACA/HTRA4-00157-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ACACA/HTRA4-00157-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ACACA/HTRA4-00157-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ACACA/HTRA4-00157-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ACACA/HTRA4-00157-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ACACA/HTRA4-00157-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ACACA/HTRA4-00157-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ACACA/HTRA4-00157-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ACACA/HTRA4-00157-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ACACA/HTRA4-00157-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ACACA/HTRA4-00157-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ACACA/HTRA4-00157-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ACACA/HTRA4-00157-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ACACA/HTRA4-00157-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ACACA/HTRA4-00157-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ACACA/HTRA4-00157-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ACACA/HTRA4-00157-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ACACA/HTRA4-00157-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ACACA/HTRA4-00157-AQAQ |
467nm;467nm |
418nm;418nm |
|
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