ABCC5-SPRR4 Gene Fusion FISH Probe
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Catalog: |
GFFP-ABCC5/SPRR4-00259 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ABCC5-SPRR4 Gene Fusion FISH Probecan detect the fusion of ABCC5 and SPRR4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ABCC5-SPRR4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
ATP Binding Cassette Subfamily C Member 5 |
Gene Summary 1 |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
Chromosome 1 |
Chromosome 3 |
Locus 1 |
3q27.1 |
Coordinates 1 |
This gene maps to 183637723-183735727 in GRCh37 coordinates. |
Gene Name 2 |
Small Proline Rich Protein 4 |
Gene Summary 2 |
The Small Proline Rich Protein 4 (SPRR4) gene is located on chr1 :152943127-152945069 at 1q21.3. |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1q21.3 |
Coordinates 2 |
This gene maps to 152943127-152945069 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ABCC5/SPRR4-00259-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ABCC5/SPRR4-00259-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ABCC5/SPRR4-00259-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ABCC5/SPRR4-00259-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ABCC5/SPRR4-00259-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ABCC5/SPRR4-00259-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ABCC5/SPRR4-00259-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ABCC5/SPRR4-00259-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ABCC5/SPRR4-00259-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ABCC5/SPRR4-00259-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ABCC5/SPRR4-00259-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ABCC5/SPRR4-00259-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ABCC5/SPRR4-00259-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ABCC5/SPRR4-00259-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ABCC5/SPRR4-00259-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ABCC5/SPRR4-00259-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ABCC5/SPRR4-00259-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ABCC5/SPRR4-00259-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ABCC5/SPRR4-00259-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ABCC5/SPRR4-00259-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ABCC5/SPRR4-00259-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ABCC5/SPRR4-00259-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ABCC5/SPRR4-00259-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ABCC5/SPRR4-00259-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ABCC5/SPRR4-00259-AQAQ |
467nm;467nm |
418nm;418nm |
|
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