AATF-LIG3 Gene Fusion FISH Probe
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Catalog: |
GFFP-AATF/LIG3-00148 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The AATF-LIG3 Gene Fusion FISH Probe can detect the fusion of AATF and LIG3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
AATF-LIG3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
DNA Ligase 3 |
Gene Summary 1 |
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q12 |
Coordinates 1 |
This gene maps to 33307516-33332088 in GRCh37 coordinates. |
Gene Name 2 |
Apoptosis Antagonizing Transcription Factor |
Gene Summary 2 |
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17q12 |
Coordinates 2 |
This gene maps to 35306174-35414171 in GRCh37 coordinates. |
Associated Diseases |
Liver Hepatocellular Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-AATF/LIG3-00148-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-AATF/LIG3-00148-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-AATF/LIG3-00148-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-AATF/LIG3-00148-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-AATF/LIG3-00148-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-AATF/LIG3-00148-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-AATF/LIG3-00148-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-AATF/LIG3-00148-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-AATF/LIG3-00148-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-AATF/LIG3-00148-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-AATF/LIG3-00148-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-AATF/LIG3-00148-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-AATF/LIG3-00148-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-AATF/LIG3-00148-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-AATF/LIG3-00148-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-AATF/LIG3-00148-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-AATF/LIG3-00148-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-AATF/LIG3-00148-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-AATF/LIG3-00148-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-AATF/LIG3-00148-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-AATF/LIG3-00148-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-AATF/LIG3-00148-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-AATF/LIG3-00148-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-AATF/LIG3-00148-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-AATF/LIG3-00148-AQAQ |
467nm;467nm |
418nm;418nm |
|
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