AAK1-WFDC13 Gene Fusion FISH Probe
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Catalog: |
GFFP-AAK1/WFDC13-00215 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The AAK1-WFDC13 Gene Fusion FISH Probecan detect the fusion of AAK1 and WFDC13 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
AAK1-WFDC13 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
AP2 Associated Kinase 1 |
Gene Summary 1 |
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 2 |
Locus 1 |
2p13.3 |
Coordinates 1 |
This gene maps to 69685126-69870977 in GRCh37 coordinates. |
Gene Name 2 |
WAP Four-disulfide Core Domain 13 |
Gene Summary 2 |
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome20 |
Locus 2 |
20q13.12 |
Coordinates 2 |
This gene maps to 44330654-44337456 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-AAK1/WFDC13-00215-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-AAK1/WFDC13-00215-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-AAK1/WFDC13-00215-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-AAK1/WFDC13-00215-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-AAK1/WFDC13-00215-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-AAK1/WFDC13-00215-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-AAK1/WFDC13-00215-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-AAK1/WFDC13-00215-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-AAK1/WFDC13-00215-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-AAK1/WFDC13-00215-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-AAK1/WFDC13-00215-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-AAK1/WFDC13-00215-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-AAK1/WFDC13-00215-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-AAK1/WFDC13-00215-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-AAK1/WFDC13-00215-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-AAK1/WFDC13-00215-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-AAK1/WFDC13-00215-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-AAK1/WFDC13-00215-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-AAK1/WFDC13-00215-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-AAK1/WFDC13-00215-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-AAK1/WFDC13-00215-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-AAK1/WFDC13-00215-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-AAK1/WFDC13-00215-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-AAK1/WFDC13-00215-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-AAK1/WFDC13-00215-AQAQ |
467nm;467nm |
418nm;418nm |
|
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