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ZNF148-MYLK Gene Fusion FISH Probe

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Catalog: GFFP-ZNF148/MYLK-13673
Classification: Gene Fusion FISH Probes
Description: The ZNF148-MYLK Gene Fusion FISH Probecan detect the fusion of ZNF148 and MYLK genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ZNF148-MYLK Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Myosin Light Chain Kinase
Gene Summary 1 This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 3
Locus 1 3q21.1
Coordinates 1 This gene maps to 123331142-123603149 in GRCh37 coordinates.
Gene Name 2 Zinc Finger Protein 148
Gene Summary 2 The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. [provided by RefSeq, Feb 2017]
Chromosome 2 Chromosome3
Locus 2 3q21.2
Coordinates 2 This gene maps to 124944512-125094198 in GRCh37 coordinates.
Associated Diseases Prostate Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ZNF148/MYLK-13673-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ZNF148/MYLK-13673-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ZNF148/MYLK-13673-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ZNF148/MYLK-13673-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ZNF148/MYLK-13673-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ZNF148/MYLK-13673-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ZNF148/MYLK-13673-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ZNF148/MYLK-13673-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ZNF148/MYLK-13673-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ZNF148/MYLK-13673-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ZNF148/MYLK-13673-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ZNF148/MYLK-13673-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ZNF148/MYLK-13673-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ZNF148/MYLK-13673-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ZNF148/MYLK-13673-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ZNF148/MYLK-13673-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ZNF148/MYLK-13673-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ZNF148/MYLK-13673-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ZNF148/MYLK-13673-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ZNF148/MYLK-13673-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ZNF148/MYLK-13673-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ZNF148/MYLK-13673-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ZNF148/MYLK-13673-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ZNF148/MYLK-13673-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ZNF148/MYLK-13673-AQAQ 467nm;467nm 418nm;418nm

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