ZMAT3-TP63 Gene Fusion FISH Probe
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Catalog: |
GFFP-ZMAT3/TP63-13373 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ZMAT3-TP63 Gene Fusion FISH Probecan detect the fusion of ZMAT3 and TP63 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ZMAT3-TP63 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Tumor Protein P63 |
Gene Summary 1 |
This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016] |
Chromosome 1 |
Chromosome 3 |
Locus 1 |
3q28 |
Coordinates 1 |
This gene maps to 189349215-189615068 in GRCh37 coordinates. |
Gene Name 2 |
Zinc Finger Matrin-type 3 |
Gene Summary 2 |
This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome3 |
Locus 2 |
3q26.32 |
Coordinates 2 |
This gene maps to 178735010-178789656 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ZMAT3/TP63-13373-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ZMAT3/TP63-13373-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ZMAT3/TP63-13373-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ZMAT3/TP63-13373-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ZMAT3/TP63-13373-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ZMAT3/TP63-13373-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ZMAT3/TP63-13373-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ZMAT3/TP63-13373-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ZMAT3/TP63-13373-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ZMAT3/TP63-13373-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ZMAT3/TP63-13373-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ZMAT3/TP63-13373-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ZMAT3/TP63-13373-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ZMAT3/TP63-13373-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ZMAT3/TP63-13373-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ZMAT3/TP63-13373-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ZMAT3/TP63-13373-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ZMAT3/TP63-13373-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ZMAT3/TP63-13373-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ZMAT3/TP63-13373-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ZMAT3/TP63-13373-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ZMAT3/TP63-13373-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ZMAT3/TP63-13373-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ZMAT3/TP63-13373-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ZMAT3/TP63-13373-AQAQ |
467nm;467nm |
418nm;418nm |
|
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