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YWHAB-BCL2L1 Gene Fusion FISH Probe

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Catalog: GFFP-YWHAB/BCL2L1-13530
Classification: Gene Fusion FISH Probes
Description: The YWHAB-BCL2L1 Gene Fusion FISH Probecan detect the fusion of YWHAB and BCL2L1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: YWHAB-BCL2L1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 BCL2 Like 1
Gene Summary 1 The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
Chromosome 1 Chromosome 20
Locus 1 20q11.21
Coordinates 1 This gene maps to 30252260-30310656 in GRCh37 coordinates.
Gene Name 2 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein Beta
Gene Summary 2 This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome20
Locus 2 20q13.12
Coordinates 2 This gene maps to 43514343-43537161 in GRCh37 coordinates.
Associated Diseases Colon Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-YWHAB/BCL2L1-13530-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-YWHAB/BCL2L1-13530-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-YWHAB/BCL2L1-13530-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-YWHAB/BCL2L1-13530-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-YWHAB/BCL2L1-13530-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-YWHAB/BCL2L1-13530-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-YWHAB/BCL2L1-13530-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-YWHAB/BCL2L1-13530-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-YWHAB/BCL2L1-13530-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-YWHAB/BCL2L1-13530-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-YWHAB/BCL2L1-13530-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-YWHAB/BCL2L1-13530-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-YWHAB/BCL2L1-13530-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-YWHAB/BCL2L1-13530-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-YWHAB/BCL2L1-13530-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-YWHAB/BCL2L1-13530-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-YWHAB/BCL2L1-13530-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-YWHAB/BCL2L1-13530-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-YWHAB/BCL2L1-13530-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-YWHAB/BCL2L1-13530-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-YWHAB/BCL2L1-13530-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-YWHAB/BCL2L1-13530-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-YWHAB/BCL2L1-13530-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-YWHAB/BCL2L1-13530-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-YWHAB/BCL2L1-13530-AQAQ 467nm;467nm 418nm;418nm

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