XPA-CORO2A Gene Fusion FISH Probe
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Catalog: |
GFFP-XPA/CORO2A-13244 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The XPA-CORO2A Gene Fusion FISH Probecan detect the fusion of XPA and CORO2A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
XPA-CORO2A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Coronin 2A |
Gene Summary 1 |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 9 |
Locus 1 |
9q22.33 |
Coordinates 1 |
This gene maps to 100883256-100954956 in GRCh37 coordinates. |
Gene Name 2 |
XPA, DNA Damage Recognition And Repair Factor |
Gene Summary 2 |
This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017] |
Chromosome 2 |
Chromosome9 |
Locus 2 |
9q22.33 |
Coordinates 2 |
This gene maps to 100437190-100459691 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-XPA/CORO2A-13244-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-XPA/CORO2A-13244-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-XPA/CORO2A-13244-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-XPA/CORO2A-13244-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-XPA/CORO2A-13244-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-XPA/CORO2A-13244-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-XPA/CORO2A-13244-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-XPA/CORO2A-13244-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-XPA/CORO2A-13244-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-XPA/CORO2A-13244-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-XPA/CORO2A-13244-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-XPA/CORO2A-13244-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-XPA/CORO2A-13244-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-XPA/CORO2A-13244-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-XPA/CORO2A-13244-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-XPA/CORO2A-13244-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-XPA/CORO2A-13244-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-XPA/CORO2A-13244-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-XPA/CORO2A-13244-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-XPA/CORO2A-13244-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-XPA/CORO2A-13244-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-XPA/CORO2A-13244-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-XPA/CORO2A-13244-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-XPA/CORO2A-13244-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-XPA/CORO2A-13244-AQAQ |
467nm;467nm |
418nm;418nm |
|
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