TRPV4-GIT2 Gene Fusion FISH Probe
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Catalog: |
GFFP-TRPV4/GIT2-14677 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The TRPV4-GIT2 Gene Fusion FISH Probecan detect the fusion of TRPV4 and GIT2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
TRPV4-GIT2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
GIT ArfGAP 2 |
Gene Summary 1 |
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12q24.11 |
Coordinates 1 |
This gene maps to 110367606-110434194 in GRCh37 coordinates. |
Gene Name 2 |
Transient Receptor Potential Cation Channel Subfamily V Member 4 |
Gene Summary 2 |
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] |
Chromosome 2 |
Chromosome12 |
Locus 2 |
12q24.11 |
Coordinates 2 |
This gene maps to 110220891-110271212 in GRCh37 coordinates. |
Associated Diseases |
Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-TRPV4/GIT2-14677-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-TRPV4/GIT2-14677-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-TRPV4/GIT2-14677-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-TRPV4/GIT2-14677-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-TRPV4/GIT2-14677-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-TRPV4/GIT2-14677-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-TRPV4/GIT2-14677-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-TRPV4/GIT2-14677-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-TRPV4/GIT2-14677-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-TRPV4/GIT2-14677-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-TRPV4/GIT2-14677-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-TRPV4/GIT2-14677-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-TRPV4/GIT2-14677-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-TRPV4/GIT2-14677-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-TRPV4/GIT2-14677-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-TRPV4/GIT2-14677-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-TRPV4/GIT2-14677-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-TRPV4/GIT2-14677-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-TRPV4/GIT2-14677-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-TRPV4/GIT2-14677-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-TRPV4/GIT2-14677-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-TRPV4/GIT2-14677-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-TRPV4/GIT2-14677-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-TRPV4/GIT2-14677-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-TRPV4/GIT2-14677-AQAQ |
467nm;467nm |
418nm;418nm |
|
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