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TRPV4-GIT2 Gene Fusion FISH Probe

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Catalog: GFFP-TRPV4/GIT2-14677
Classification: Gene Fusion FISH Probes
Description: The TRPV4-GIT2 Gene Fusion FISH Probecan detect the fusion of TRPV4 and GIT2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: TRPV4-GIT2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 GIT ArfGAP 2
Gene Summary 1 This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008]
Chromosome 1 Chromosome 12
Locus 1 12q24.11
Coordinates 1 This gene maps to 110367606-110434194 in GRCh37 coordinates.
Gene Name 2 Transient Receptor Potential Cation Channel Subfamily V Member 4
Gene Summary 2 This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Chromosome 2 Chromosome12
Locus 2 12q24.11
Coordinates 2 This gene maps to 110220891-110271212 in GRCh37 coordinates.
Associated Diseases Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-TRPV4/GIT2-14677-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-TRPV4/GIT2-14677-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-TRPV4/GIT2-14677-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-TRPV4/GIT2-14677-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-TRPV4/GIT2-14677-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-TRPV4/GIT2-14677-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-TRPV4/GIT2-14677-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-TRPV4/GIT2-14677-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-TRPV4/GIT2-14677-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-TRPV4/GIT2-14677-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-TRPV4/GIT2-14677-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-TRPV4/GIT2-14677-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-TRPV4/GIT2-14677-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-TRPV4/GIT2-14677-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-TRPV4/GIT2-14677-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-TRPV4/GIT2-14677-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-TRPV4/GIT2-14677-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-TRPV4/GIT2-14677-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-TRPV4/GIT2-14677-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-TRPV4/GIT2-14677-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-TRPV4/GIT2-14677-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-TRPV4/GIT2-14677-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-TRPV4/GIT2-14677-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-TRPV4/GIT2-14677-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-TRPV4/GIT2-14677-AQAQ 467nm;467nm 418nm;418nm

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