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SPTBN2-PC Gene Fusion FISH Probe

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Catalog: GFFP-SPTBN2/PC-11527
Classification: Gene Fusion FISH Probes
Description: The SPTBN2-PC Gene Fusion FISH Probecan detect the fusion of SPTBN2 and PC genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SPTBN2-PC Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Pyruvate Carboxylase
Gene Summary 1 This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 11
Locus 1 11q13.2
Coordinates 1 This gene maps to 66615996-66725847 in GRCh37 coordinates.
Gene Name 2 Spectrin Beta, Non-erythrocytic 2
Gene Summary 2 Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
Chromosome 2 Chromosome11
Locus 2 11q13.2
Coordinates 2 This gene maps to 66452719-66488870 in GRCh37 coordinates.
Associated Diseases Esophageal Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SPTBN2/PC-11527-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SPTBN2/PC-11527-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SPTBN2/PC-11527-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SPTBN2/PC-11527-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SPTBN2/PC-11527-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SPTBN2/PC-11527-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SPTBN2/PC-11527-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SPTBN2/PC-11527-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SPTBN2/PC-11527-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SPTBN2/PC-11527-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SPTBN2/PC-11527-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SPTBN2/PC-11527-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SPTBN2/PC-11527-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SPTBN2/PC-11527-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SPTBN2/PC-11527-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SPTBN2/PC-11527-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SPTBN2/PC-11527-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SPTBN2/PC-11527-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SPTBN2/PC-11527-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SPTBN2/PC-11527-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SPTBN2/PC-11527-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SPTBN2/PC-11527-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SPTBN2/PC-11527-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SPTBN2/PC-11527-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SPTBN2/PC-11527-AQAQ 467nm;467nm 418nm;418nm

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