SPO11-GSTA1 Gene Fusion FISH Probe
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Catalog: |
GFFP-SPO11/GSTA1-11244 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SPO11-GSTA1 Gene Fusion FISH Probecan detect the fusion of SPO11 and GSTA1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SPO11-GSTA1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Glutathione S-transferase Alpha 1 |
Gene Summary 1 |
This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
Chromosome 1 |
Chromosome 6 |
Locus 1 |
6p12.2 |
Coordinates 1 |
This gene maps to 52656177-52668664 in GRCh37 coordinates. |
Gene Name 2 |
SPO11, Initiator Of Meiotic Double Stranded Breaks |
Gene Summary 2 |
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome20 |
Locus 2 |
20q13.31 |
Coordinates 2 |
This gene maps to 55904830-55919049 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SPO11/GSTA1-11244-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SPO11/GSTA1-11244-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SPO11/GSTA1-11244-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SPO11/GSTA1-11244-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SPO11/GSTA1-11244-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SPO11/GSTA1-11244-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SPO11/GSTA1-11244-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SPO11/GSTA1-11244-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SPO11/GSTA1-11244-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SPO11/GSTA1-11244-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SPO11/GSTA1-11244-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SPO11/GSTA1-11244-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SPO11/GSTA1-11244-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SPO11/GSTA1-11244-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SPO11/GSTA1-11244-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SPO11/GSTA1-11244-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SPO11/GSTA1-11244-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SPO11/GSTA1-11244-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SPO11/GSTA1-11244-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SPO11/GSTA1-11244-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SPO11/GSTA1-11244-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SPO11/GSTA1-11244-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SPO11/GSTA1-11244-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SPO11/GSTA1-11244-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SPO11/GSTA1-11244-AQAQ |
467nm;467nm |
418nm;418nm |
|
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