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SORBS2-MRPS35 Gene Fusion FISH Probe

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Catalog: GFFP-SORBS2/MRPS35-11326
Classification: Gene Fusion FISH Probes
Description: The SORBS2-MRPS35 Gene Fusion FISH Probecan detect the fusion of SORBS2 and MRPS35 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SORBS2-MRPS35 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Sorbin And SH3 Domain Containing 2
Gene Summary 1 Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 4
Locus 1 4q35.1
Coordinates 1 This gene maps to 186506597-186877870 in GRCh37 coordinates.
Gene Name 2 Mitochondrial Ribosomal Protein S35
Gene Summary 2 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 3p, 5q, and 10q. [provided by RefSeq, Jul 2010]
Chromosome 2 Chromosome12
Locus 2 12p11.22
Coordinates 2 This gene maps to 27863705-27909237 in GRCh37 coordinates.
Associated Diseases Prostate Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SORBS2/MRPS35-11326-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SORBS2/MRPS35-11326-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SORBS2/MRPS35-11326-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SORBS2/MRPS35-11326-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SORBS2/MRPS35-11326-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SORBS2/MRPS35-11326-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SORBS2/MRPS35-11326-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SORBS2/MRPS35-11326-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SORBS2/MRPS35-11326-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SORBS2/MRPS35-11326-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SORBS2/MRPS35-11326-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SORBS2/MRPS35-11326-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SORBS2/MRPS35-11326-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SORBS2/MRPS35-11326-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SORBS2/MRPS35-11326-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SORBS2/MRPS35-11326-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SORBS2/MRPS35-11326-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SORBS2/MRPS35-11326-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SORBS2/MRPS35-11326-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SORBS2/MRPS35-11326-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SORBS2/MRPS35-11326-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SORBS2/MRPS35-11326-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SORBS2/MRPS35-11326-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SORBS2/MRPS35-11326-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SORBS2/MRPS35-11326-AQAQ 467nm;467nm 418nm;418nm

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