SOCS6-GLIS3 Gene Fusion FISH Probe
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Catalog: |
GFFP-SOCS6/GLIS3-11337 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SOCS6-GLIS3 Gene Fusion FISH Probecan detect the fusion of SOCS6 and GLIS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SOCS6-GLIS3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Suppressor Of Cytokine Signaling 6 |
Gene Summary 1 |
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 18 |
Locus 1 |
18q22.2 |
Coordinates 1 |
This gene maps to 67956136-67997434 in GRCh37 coordinates. |
Gene Name 2 |
GLIS Family Zinc Finger 3 |
Gene Summary 2 |
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome9 |
Locus 2 |
9p24.2 |
Coordinates 2 |
This gene maps to 3824127-4300035 in GRCh37 coordinates. |
Associated Diseases |
Uterine Corpus Endometrial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SOCS6/GLIS3-11337-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SOCS6/GLIS3-11337-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SOCS6/GLIS3-11337-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SOCS6/GLIS3-11337-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SOCS6/GLIS3-11337-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SOCS6/GLIS3-11337-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SOCS6/GLIS3-11337-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SOCS6/GLIS3-11337-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SOCS6/GLIS3-11337-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SOCS6/GLIS3-11337-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SOCS6/GLIS3-11337-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SOCS6/GLIS3-11337-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SOCS6/GLIS3-11337-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SOCS6/GLIS3-11337-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SOCS6/GLIS3-11337-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SOCS6/GLIS3-11337-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SOCS6/GLIS3-11337-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SOCS6/GLIS3-11337-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SOCS6/GLIS3-11337-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SOCS6/GLIS3-11337-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SOCS6/GLIS3-11337-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SOCS6/GLIS3-11337-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SOCS6/GLIS3-11337-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SOCS6/GLIS3-11337-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SOCS6/GLIS3-11337-AQAQ |
467nm;467nm |
418nm;418nm |
|
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