SNX8-KDELR2 Gene Fusion FISH Probe
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Catalog: |
GFFP-SNX8/KDELR2-11345 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The SNX8-KDELR2 Gene Fusion FISH Probecan detect the fusion of SNX8 and KDELR2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
SNX8-KDELR2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
KDEL Endoplasmic Reticulum Protein Retention Receptor 2 |
Gene Summary 1 |
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 7 |
Locus 1 |
7p22.1 |
Coordinates 1 |
This gene maps to 6500711-6523849 in GRCh37 coordinates. |
Gene Name 2 |
Sorting Nexin 8 |
Gene Summary 2 |
The Sorting Nexin 8 (SNX8) gene is located on chr7 :2291404-2354099 at 7p22.3. |
Chromosome 2 |
Chromosome7 |
Locus 2 |
7p22.3 |
Coordinates 2 |
This gene maps to 2291404-2354099 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-SNX8/KDELR2-11345-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-SNX8/KDELR2-11345-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-SNX8/KDELR2-11345-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-SNX8/KDELR2-11345-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-SNX8/KDELR2-11345-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-SNX8/KDELR2-11345-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-SNX8/KDELR2-11345-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-SNX8/KDELR2-11345-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-SNX8/KDELR2-11345-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-SNX8/KDELR2-11345-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-SNX8/KDELR2-11345-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-SNX8/KDELR2-11345-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-SNX8/KDELR2-11345-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-SNX8/KDELR2-11345-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-SNX8/KDELR2-11345-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-SNX8/KDELR2-11345-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-SNX8/KDELR2-11345-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-SNX8/KDELR2-11345-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-SNX8/KDELR2-11345-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-SNX8/KDELR2-11345-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-SNX8/KDELR2-11345-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-SNX8/KDELR2-11345-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-SNX8/KDELR2-11345-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-SNX8/KDELR2-11345-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-SNX8/KDELR2-11345-AQAQ |
467nm;467nm |
418nm;418nm |
|
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