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SNRPN-CYFIP1 Gene Fusion FISH Probe

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Catalog: GFFP-SNRPN/CYFIP1-11096
Classification: Gene Fusion FISH Probes
Description: The SNRPN-CYFIP1 Gene Fusion FISH Probecan detect the fusion of SNRPN and CYFIP1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SNRPN-CYFIP1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Small Nuclear Ribonucleoprotein Polypeptide N
Gene Summary 1 This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017]
Chromosome 1 Chromosome 15
Locus 1 15q11.2
Coordinates 1 This gene maps to 25068793-25223729 in GRCh37 coordinates.
Gene Name 2 Cytoplasmic FMR1 Interacting Protein 1
Gene Summary 2 This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization.This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, May 2017]
Chromosome 2 Chromosome15
Locus 2 15q11.2
Coordinates 2 This gene maps to 22892683-23003603 in GRCh37 coordinates.
Associated Diseases Brain Lower Grade Glioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SNRPN/CYFIP1-11096-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SNRPN/CYFIP1-11096-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SNRPN/CYFIP1-11096-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SNRPN/CYFIP1-11096-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SNRPN/CYFIP1-11096-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SNRPN/CYFIP1-11096-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SNRPN/CYFIP1-11096-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SNRPN/CYFIP1-11096-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SNRPN/CYFIP1-11096-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SNRPN/CYFIP1-11096-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SNRPN/CYFIP1-11096-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SNRPN/CYFIP1-11096-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SNRPN/CYFIP1-11096-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SNRPN/CYFIP1-11096-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SNRPN/CYFIP1-11096-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SNRPN/CYFIP1-11096-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SNRPN/CYFIP1-11096-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SNRPN/CYFIP1-11096-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SNRPN/CYFIP1-11096-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SNRPN/CYFIP1-11096-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SNRPN/CYFIP1-11096-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SNRPN/CYFIP1-11096-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SNRPN/CYFIP1-11096-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SNRPN/CYFIP1-11096-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SNRPN/CYFIP1-11096-AQAQ 467nm;467nm 418nm;418nm

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