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SMU1-B4GALT1 Gene Fusion FISH Probe

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Catalog: GFFP-SMU1/B4GALT1-14596
Classification: Gene Fusion FISH Probes
Description: The SMU1-B4GALT1 Gene Fusion FISH Probecan detect the fusion of SMU1 and B4GALT1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SMU1-B4GALT1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Beta-1,4-galactosyltransferase 1
Gene Summary 1 This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 9
Locus 1 9p21.1
Coordinates 1 This gene maps to 33110638-33167356 in GRCh37 coordinates.
Gene Name 2 SMU1, DNA Replication Regulator And Spliceosomal Factor
Gene Summary 2 The SMU1, DNA Replication Regulator And Spliceosomal Factor (SMU1) gene is located on chr9 :33041849-33076714 at 9p21.1.
Chromosome 2 Chromosome9
Locus 2 9p21.1
Coordinates 2 This gene maps to 33041849-33076714 in GRCh37 coordinates.
Associated Diseases Head And Neck Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SMU1/B4GALT1-14596-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SMU1/B4GALT1-14596-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SMU1/B4GALT1-14596-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SMU1/B4GALT1-14596-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SMU1/B4GALT1-14596-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SMU1/B4GALT1-14596-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SMU1/B4GALT1-14596-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SMU1/B4GALT1-14596-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SMU1/B4GALT1-14596-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SMU1/B4GALT1-14596-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SMU1/B4GALT1-14596-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SMU1/B4GALT1-14596-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SMU1/B4GALT1-14596-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SMU1/B4GALT1-14596-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SMU1/B4GALT1-14596-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SMU1/B4GALT1-14596-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SMU1/B4GALT1-14596-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SMU1/B4GALT1-14596-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SMU1/B4GALT1-14596-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SMU1/B4GALT1-14596-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SMU1/B4GALT1-14596-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SMU1/B4GALT1-14596-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SMU1/B4GALT1-14596-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SMU1/B4GALT1-14596-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SMU1/B4GALT1-14596-AQAQ 467nm;467nm 418nm;418nm

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