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SENP6-ACACB Gene Fusion FISH Probe

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Catalog: GFFP-SENP6/ACACB-10653
Classification: Gene Fusion FISH Probes
Description: The SENP6-ACACB Gene Fusion FISH Probecan detect the fusion of SENP6 and ACACB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SENP6-ACACB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Acetyl-CoA Carboxylase Beta
Gene Summary 1 Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 12
Locus 1 12q24.11
Coordinates 1 This gene maps to 109577201-109706030 in GRCh37 coordinates.
Gene Name 2 SUMO1/sentrin Specific Peptidase 6
Gene Summary 2 Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]
Chromosome 2 Chromosome6
Locus 2 6q14.1
Coordinates 2 This gene maps to 76311621-76427994 in GRCh37 coordinates.
Associated Diseases Prostate Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SENP6/ACACB-10653-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SENP6/ACACB-10653-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SENP6/ACACB-10653-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SENP6/ACACB-10653-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SENP6/ACACB-10653-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SENP6/ACACB-10653-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SENP6/ACACB-10653-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SENP6/ACACB-10653-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SENP6/ACACB-10653-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SENP6/ACACB-10653-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SENP6/ACACB-10653-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SENP6/ACACB-10653-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SENP6/ACACB-10653-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SENP6/ACACB-10653-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SENP6/ACACB-10653-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SENP6/ACACB-10653-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SENP6/ACACB-10653-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SENP6/ACACB-10653-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SENP6/ACACB-10653-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SENP6/ACACB-10653-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SENP6/ACACB-10653-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SENP6/ACACB-10653-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SENP6/ACACB-10653-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SENP6/ACACB-10653-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SENP6/ACACB-10653-AQAQ 467nm;467nm 418nm;418nm

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