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SAE1-HAS1 Gene Fusion FISH Probe

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Catalog: GFFP-SAE1/HAS1-10530
Classification: Gene Fusion FISH Probes
Description: The SAE1-HAS1 Gene Fusion FISH Probecan detect the fusion of SAE1 and HAS1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: SAE1-HAS1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Hyaluronan Synthase 1
Gene Summary 1 Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Chromosome 1 Chromosome 19
Locus 1 19q13.41
Coordinates 1 This gene maps to 52216364-52227221 in GRCh37 coordinates.
Gene Name 2 SUMO1 Activating Enzyme Subunit 1
Gene Summary 2 Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]
Chromosome 2 Chromosome19
Locus 2 19q13.32
Coordinates 2 This gene maps to 47634079-47713893 in GRCh37 coordinates.
Associated Diseases Sarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-SAE1/HAS1-10530-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-SAE1/HAS1-10530-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-SAE1/HAS1-10530-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-SAE1/HAS1-10530-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-SAE1/HAS1-10530-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-SAE1/HAS1-10530-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-SAE1/HAS1-10530-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-SAE1/HAS1-10530-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-SAE1/HAS1-10530-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-SAE1/HAS1-10530-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-SAE1/HAS1-10530-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-SAE1/HAS1-10530-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-SAE1/HAS1-10530-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-SAE1/HAS1-10530-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-SAE1/HAS1-10530-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-SAE1/HAS1-10530-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-SAE1/HAS1-10530-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-SAE1/HAS1-10530-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-SAE1/HAS1-10530-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-SAE1/HAS1-10530-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-SAE1/HAS1-10530-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-SAE1/HAS1-10530-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-SAE1/HAS1-10530-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-SAE1/HAS1-10530-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-SAE1/HAS1-10530-AQAQ 467nm;467nm 418nm;418nm

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