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ROBO1-HECW2 Gene Fusion FISH Probe

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Catalog: GFFP-ROBO1/HECW2-10384
Classification: Gene Fusion FISH Probes
Description: The ROBO1-HECW2 Gene Fusion FISH Probecan detect the fusion of ROBO1 and HECW2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ROBO1-HECW2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Roundabout Guidance Receptor 1
Gene Summary 1 Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Chromosome 1 Chromosome 3
Locus 1 3p12.3
Coordinates 1 This gene maps to 78646387-79817059 in GRCh37 coordinates.
Gene Name 2 HECT, C2 And WW Domain Containing E3 Ubiquitin Protein Ligase 2
Gene Summary 2 This gene encodes a member of a family of E3 ubiquitin ligases which plays an important role in the proliferation, migration and differentiation of neural crest cells as a regulator of glial cell line-derived neurotrophic factor (GDNF)/Ret signaling. This gene also plays an important role in angiogenesis through stabilization of endothelial cell-to-cell junctions as a regulator of angiomotin-like 1 stability. The encoded protein contains an N-terminal calcium/lipid-binding (C2) domain involved in membrane targeting, two-four WW domains responsible for cellular localization and substrate recognition, and a C-terminal homologous with E6-associated protein C-terminus (HECT) catalytic domain. Naturally occurring mutations in this gene are associated with neurodevelopmental delay, hypotonia, and epilepsy. The decreased expression of this gene in the aganglionic colon is associated with Hirschsprung's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Chromosome 2 Chromosome2
Locus 2 2q32.3
Coordinates 2 This gene maps to 197063976-197457335 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ROBO1/HECW2-10384-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ROBO1/HECW2-10384-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ROBO1/HECW2-10384-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ROBO1/HECW2-10384-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ROBO1/HECW2-10384-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ROBO1/HECW2-10384-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ROBO1/HECW2-10384-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ROBO1/HECW2-10384-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ROBO1/HECW2-10384-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ROBO1/HECW2-10384-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ROBO1/HECW2-10384-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ROBO1/HECW2-10384-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ROBO1/HECW2-10384-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ROBO1/HECW2-10384-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ROBO1/HECW2-10384-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ROBO1/HECW2-10384-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ROBO1/HECW2-10384-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ROBO1/HECW2-10384-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ROBO1/HECW2-10384-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ROBO1/HECW2-10384-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ROBO1/HECW2-10384-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ROBO1/HECW2-10384-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ROBO1/HECW2-10384-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ROBO1/HECW2-10384-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ROBO1/HECW2-10384-AQAQ 467nm;467nm 418nm;418nm

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