RFX7-PCSK6 Gene Fusion FISH Probe
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Catalog: |
GFFP-RFX7/PCSK6-09866 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RFX7-PCSK6 Gene Fusion FISH Probecan detect the fusion of RFX7 and PCSK6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RFX7-PCSK6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Proprotein Convertase Subtilisin/kexin Type 6 |
Gene Summary 1 |
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2014] |
Chromosome 1 |
Chromosome 15 |
Locus 1 |
15q26.3 |
Coordinates 1 |
This gene maps to 101844132-102030187 in GRCh37 coordinates. |
Gene Name 2 |
Regulatory Factor X7 |
Gene Summary 2 |
RFX7 is a member of the regulatory factor X (RFX) family of transcription factors (see RFX1, MIM 600006) (Aftab et al., 2008 [PubMed 18673564]).[supplied by OMIM, Mar 2009] |
Chromosome 2 |
Chromosome15 |
Locus 2 |
15q21.3 |
Coordinates 2 |
This gene maps to 56382730-56535483 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RFX7/PCSK6-09866-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RFX7/PCSK6-09866-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RFX7/PCSK6-09866-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RFX7/PCSK6-09866-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RFX7/PCSK6-09866-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RFX7/PCSK6-09866-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RFX7/PCSK6-09866-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RFX7/PCSK6-09866-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RFX7/PCSK6-09866-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RFX7/PCSK6-09866-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RFX7/PCSK6-09866-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RFX7/PCSK6-09866-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RFX7/PCSK6-09866-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RFX7/PCSK6-09866-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RFX7/PCSK6-09866-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RFX7/PCSK6-09866-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RFX7/PCSK6-09866-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RFX7/PCSK6-09866-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RFX7/PCSK6-09866-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RFX7/PCSK6-09866-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RFX7/PCSK6-09866-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RFX7/PCSK6-09866-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RFX7/PCSK6-09866-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RFX7/PCSK6-09866-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RFX7/PCSK6-09866-AQAQ |
467nm;467nm |
418nm;418nm |
|
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