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RANBP9-ATXN1 Gene Fusion FISH Probe

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Catalog: GFFP-RANBP9/ATXN1-09769
Classification: Gene Fusion FISH Probes
Description: The RANBP9-ATXN1 Gene Fusion FISH Probecan detect the fusion of RANBP9 and ATXN1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RANBP9-ATXN1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Ataxin 1
Gene Summary 1 The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 40-83 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). Alternative splicing results in multiple transcript variants, with one variant encoding multiple distinct proteins, ATXN1 and Alt-ATXN1, due to the use of overlapping alternate reading frames. [provided by RefSeq, Nov 2017]
Chromosome 1 Chromosome 6
Locus 1 6p22.3
Coordinates 1 This gene maps to 16299342-16761721 in GRCh37 coordinates.
Gene Name 2 RAN Binding Protein 9
Gene Summary 2 This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome6
Locus 2 6p23
Coordinates 2 This gene maps to 13621729-13711796 in GRCh37 coordinates.
Associated Diseases Brain Lower Grade Glioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RANBP9/ATXN1-09769-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RANBP9/ATXN1-09769-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RANBP9/ATXN1-09769-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RANBP9/ATXN1-09769-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RANBP9/ATXN1-09769-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RANBP9/ATXN1-09769-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RANBP9/ATXN1-09769-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RANBP9/ATXN1-09769-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RANBP9/ATXN1-09769-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RANBP9/ATXN1-09769-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RANBP9/ATXN1-09769-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RANBP9/ATXN1-09769-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RANBP9/ATXN1-09769-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RANBP9/ATXN1-09769-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RANBP9/ATXN1-09769-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RANBP9/ATXN1-09769-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RANBP9/ATXN1-09769-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RANBP9/ATXN1-09769-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RANBP9/ATXN1-09769-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RANBP9/ATXN1-09769-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RANBP9/ATXN1-09769-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RANBP9/ATXN1-09769-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RANBP9/ATXN1-09769-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RANBP9/ATXN1-09769-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RANBP9/ATXN1-09769-AQAQ 467nm;467nm 418nm;418nm

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