RANBP2-BMP5 Gene Fusion FISH Probe
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Catalog: |
GFFP-RANBP2/BMP5-09771 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The RANBP2-BMP5 Gene Fusion FISH Probecan detect the fusion of RANBP2 and BMP5 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
RANBP2-BMP5 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Bone Morphogenetic Protein 5 |
Gene Summary 1 |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016] |
Chromosome 1 |
Chromosome 6 |
Locus 1 |
6p12.1 |
Coordinates 1 |
This gene maps to 55620237-55740375 in GRCh37 coordinates. |
Gene Name 2 |
RAN Binding Protein 2 |
Gene Summary 2 |
RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome2 |
Locus 2 |
2q13 |
Coordinates 2 |
This gene maps to 109335936-109402267 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-RANBP2/BMP5-09771-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-RANBP2/BMP5-09771-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-RANBP2/BMP5-09771-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-RANBP2/BMP5-09771-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-RANBP2/BMP5-09771-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-RANBP2/BMP5-09771-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-RANBP2/BMP5-09771-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-RANBP2/BMP5-09771-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-RANBP2/BMP5-09771-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-RANBP2/BMP5-09771-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-RANBP2/BMP5-09771-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-RANBP2/BMP5-09771-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-RANBP2/BMP5-09771-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-RANBP2/BMP5-09771-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-RANBP2/BMP5-09771-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-RANBP2/BMP5-09771-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-RANBP2/BMP5-09771-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-RANBP2/BMP5-09771-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-RANBP2/BMP5-09771-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-RANBP2/BMP5-09771-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-RANBP2/BMP5-09771-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-RANBP2/BMP5-09771-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-RANBP2/BMP5-09771-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-RANBP2/BMP5-09771-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-RANBP2/BMP5-09771-AQAQ |
467nm;467nm |
418nm;418nm |
|
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