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RAD18-CD86 Gene Fusion FISH Probe

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Catalog: GFFP-RAD18/CD86-09829
Classification: Gene Fusion FISH Probes
Description: The RAD18-CD86 Gene Fusion FISH Probecan detect the fusion of RAD18 and CD86 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RAD18-CD86 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 CD86 Molecule
Gene Summary 1 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Chromosome 1 Chromosome 3
Locus 1 3q13.33
Coordinates 1 This gene maps to 121774208-121839988 in GRCh37 coordinates.
Gene Name 2 RAD18, E3 Ubiquitin Protein Ligase
Gene Summary 2 The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome3
Locus 2 3p25.3
Coordinates 2 This gene maps to 8918879-9005159 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RAD18/CD86-09829-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RAD18/CD86-09829-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RAD18/CD86-09829-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RAD18/CD86-09829-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RAD18/CD86-09829-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RAD18/CD86-09829-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RAD18/CD86-09829-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RAD18/CD86-09829-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RAD18/CD86-09829-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RAD18/CD86-09829-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RAD18/CD86-09829-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RAD18/CD86-09829-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RAD18/CD86-09829-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RAD18/CD86-09829-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RAD18/CD86-09829-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RAD18/CD86-09829-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RAD18/CD86-09829-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RAD18/CD86-09829-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RAD18/CD86-09829-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RAD18/CD86-09829-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RAD18/CD86-09829-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RAD18/CD86-09829-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RAD18/CD86-09829-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RAD18/CD86-09829-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RAD18/CD86-09829-AQAQ 467nm;467nm 418nm;418nm

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