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RAD17-SEC24A Gene Fusion FISH Probe

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Catalog: GFFP-RAD17/SEC24A-09831
Classification: Gene Fusion FISH Probes
Description: The RAD17-SEC24A Gene Fusion FISH Probecan detect the fusion of RAD17 and SEC24A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RAD17-SEC24A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 RAD17 Checkpoint Clamp Loader Component
Gene Summary 1 The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013]
Chromosome 1 Chromosome 5
Locus 1 5q13.2
Coordinates 1 This gene maps to 68665123-68710630 in GRCh37 coordinates.
Gene Name 2 SEC24 Homolog A, COPII Coat Complex Component
Gene Summary 2 The protein encoded by this gene belongs to a family of proteins that are homologous to yeast Sec24. This protein is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Chromosome 2 Chromosome5
Locus 2 5q31.1
Coordinates 2 This gene maps to 133984478-134063601 in GRCh37 coordinates.
Associated Diseases Prostate Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RAD17/SEC24A-09831-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RAD17/SEC24A-09831-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RAD17/SEC24A-09831-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RAD17/SEC24A-09831-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RAD17/SEC24A-09831-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RAD17/SEC24A-09831-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RAD17/SEC24A-09831-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RAD17/SEC24A-09831-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RAD17/SEC24A-09831-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RAD17/SEC24A-09831-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RAD17/SEC24A-09831-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RAD17/SEC24A-09831-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RAD17/SEC24A-09831-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RAD17/SEC24A-09831-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RAD17/SEC24A-09831-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RAD17/SEC24A-09831-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RAD17/SEC24A-09831-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RAD17/SEC24A-09831-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RAD17/SEC24A-09831-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RAD17/SEC24A-09831-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RAD17/SEC24A-09831-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RAD17/SEC24A-09831-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RAD17/SEC24A-09831-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RAD17/SEC24A-09831-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RAD17/SEC24A-09831-AQAQ 467nm;467nm 418nm;418nm

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