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RAB40C-MYH11 Gene Fusion FISH Probe

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Catalog: GFFP-RAB40C/MYH11-09553
Classification: Gene Fusion FISH Probes
Description: The RAB40C-MYH11 Gene Fusion FISH Probecan detect the fusion of RAB40C and MYH11 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: RAB40C-MYH11 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Myosin Heavy Chain 11
Gene Summary 1 The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 16
Locus 1 16p13.11
Coordinates 1 This gene maps to 15796991-15950887 in GRCh37 coordinates.
Gene Name 2 RAB40C, Member RAS Oncogene Family
Gene Summary 2 The RAB40C, Member RAS Oncogene Family (RAB40C) gene is located on chr16 :639356-679273 at 16p13.3.
Chromosome 2 Chromosome16
Locus 2 16p13.3
Coordinates 2 This gene maps to 639356-679273 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-RAB40C/MYH11-09553-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-RAB40C/MYH11-09553-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-RAB40C/MYH11-09553-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-RAB40C/MYH11-09553-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-RAB40C/MYH11-09553-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-RAB40C/MYH11-09553-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-RAB40C/MYH11-09553-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-RAB40C/MYH11-09553-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-RAB40C/MYH11-09553-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-RAB40C/MYH11-09553-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-RAB40C/MYH11-09553-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-RAB40C/MYH11-09553-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-RAB40C/MYH11-09553-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-RAB40C/MYH11-09553-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-RAB40C/MYH11-09553-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-RAB40C/MYH11-09553-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-RAB40C/MYH11-09553-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-RAB40C/MYH11-09553-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-RAB40C/MYH11-09553-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-RAB40C/MYH11-09553-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-RAB40C/MYH11-09553-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-RAB40C/MYH11-09553-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-RAB40C/MYH11-09553-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-RAB40C/MYH11-09553-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-RAB40C/MYH11-09553-AQAQ 467nm;467nm 418nm;418nm

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