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PTPN21-TTC8 Gene Fusion FISH Probe

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Catalog: GFFP-PTPN21/TTC8-09359
Classification: Gene Fusion FISH Probes
Description: The PTPN21-TTC8 Gene Fusion FISH Probecan detect the fusion of PTPN21 and TTC8 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PTPN21-TTC8 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Protein Tyrosine Phosphatase, Non-receptor Type 21
Gene Summary 1 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 14
Locus 1 14q31.3
Coordinates 1 This gene maps to 88932121-89021123 in GRCh37 coordinates.
Gene Name 2 Tetratricopeptide Repeat Domain 8
Gene Summary 2 This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. A mutation in this gene has also been implicated in nonsyndromic retinitis pigmentosa. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Chromosome 2 Chromosome14
Locus 2 14q31.3
Coordinates 2 This gene maps to 89290977-89344335 in GRCh37 coordinates.
Associated Diseases Kidney Renal Papillary Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PTPN21/TTC8-09359-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PTPN21/TTC8-09359-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PTPN21/TTC8-09359-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PTPN21/TTC8-09359-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PTPN21/TTC8-09359-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PTPN21/TTC8-09359-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PTPN21/TTC8-09359-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PTPN21/TTC8-09359-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PTPN21/TTC8-09359-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PTPN21/TTC8-09359-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PTPN21/TTC8-09359-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PTPN21/TTC8-09359-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PTPN21/TTC8-09359-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PTPN21/TTC8-09359-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PTPN21/TTC8-09359-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PTPN21/TTC8-09359-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PTPN21/TTC8-09359-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PTPN21/TTC8-09359-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PTPN21/TTC8-09359-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PTPN21/TTC8-09359-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PTPN21/TTC8-09359-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PTPN21/TTC8-09359-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PTPN21/TTC8-09359-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PTPN21/TTC8-09359-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PTPN21/TTC8-09359-AQAQ 467nm;467nm 418nm;418nm

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