PSME1-AP1G2 Gene Fusion FISH Probe
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Catalog: |
GFFP-PSME1/AP1G2-09436 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PSME1-AP1G2 Gene Fusion FISH Probecan detect the fusion of PSME1 and AP1G2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PSME1-AP1G2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Proteasome Activator Subunit 1 |
Gene Summary 1 |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Chromosome 1 |
Chromosome 14 |
Locus 1 |
14q12 |
Coordinates 1 |
This gene maps to 24605377-24608176 in GRCh37 coordinates. |
Gene Name 2 |
Adaptor Related Protein Complex 1 Gamma 2 Subunit |
Gene Summary 2 |
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. [provided by RefSeq, Aug 2017] |
Chromosome 2 |
Chromosome14 |
Locus 2 |
14q11.2 |
Coordinates 2 |
This gene maps to 24028776-24037279 in GRCh37 coordinates. |
Associated Diseases |
Kidney Renal Papillary Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PSME1/AP1G2-09436-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PSME1/AP1G2-09436-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PSME1/AP1G2-09436-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PSME1/AP1G2-09436-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PSME1/AP1G2-09436-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PSME1/AP1G2-09436-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PSME1/AP1G2-09436-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PSME1/AP1G2-09436-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PSME1/AP1G2-09436-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PSME1/AP1G2-09436-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PSME1/AP1G2-09436-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PSME1/AP1G2-09436-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PSME1/AP1G2-09436-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PSME1/AP1G2-09436-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PSME1/AP1G2-09436-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PSME1/AP1G2-09436-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PSME1/AP1G2-09436-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PSME1/AP1G2-09436-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PSME1/AP1G2-09436-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PSME1/AP1G2-09436-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PSME1/AP1G2-09436-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PSME1/AP1G2-09436-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PSME1/AP1G2-09436-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PSME1/AP1G2-09436-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PSME1/AP1G2-09436-AQAQ |
467nm;467nm |
418nm;418nm |
|
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