banner
  • Home
  • PPP4R1-PAWR Gene Fusion FISH Probe

PPP4R1-PAWR Gene Fusion FISH Probe

Add to Cart
Catalog: GFFP-PPP4R1/PAWR-14454
Classification: Gene Fusion FISH Probes
Description: The PPP4R1-PAWR Gene Fusion FISH Probecan detect the fusion of PPP4R1 and PAWR genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PPP4R1-PAWR Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Pro-apoptotic WT1 Regulator
Gene Summary 1 This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017]
Chromosome 1 Chromosome 12
Locus 1 12q21.2
Coordinates 1 This gene maps to 79985744-80084790 in GRCh37 coordinates.
Gene Name 2 Protein Phosphatase 4 Regulatory Subunit 1
Gene Summary 2 This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Chromosome 2 Chromosome18
Locus 2 18p11.22
Coordinates 2 This gene maps to 9546791-9614600 in GRCh37 coordinates.
Associated Diseases Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PPP4R1/PAWR-14454-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PPP4R1/PAWR-14454-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PPP4R1/PAWR-14454-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PPP4R1/PAWR-14454-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PPP4R1/PAWR-14454-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PPP4R1/PAWR-14454-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PPP4R1/PAWR-14454-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PPP4R1/PAWR-14454-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PPP4R1/PAWR-14454-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PPP4R1/PAWR-14454-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PPP4R1/PAWR-14454-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PPP4R1/PAWR-14454-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PPP4R1/PAWR-14454-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PPP4R1/PAWR-14454-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PPP4R1/PAWR-14454-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PPP4R1/PAWR-14454-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PPP4R1/PAWR-14454-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PPP4R1/PAWR-14454-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PPP4R1/PAWR-14454-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PPP4R1/PAWR-14454-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PPP4R1/PAWR-14454-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PPP4R1/PAWR-14454-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PPP4R1/PAWR-14454-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PPP4R1/PAWR-14454-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PPP4R1/PAWR-14454-AQAQ 467nm;467nm 418nm;418nm

Other Products

Online Inquiry

Order

0
Inquiry Basket ( 0 ) Choose Dye*