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PPP2R4-PAX5 Gene Fusion FISH Probe

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Catalog: GFFP-PPP2R4/PAX5-09267
Classification: Gene Fusion FISH Probes
Description: The PPP2R4-PAX5 Gene Fusion FISH Probecan detect the fusion of PPP2R4 and PAX5 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PPP2R4-PAX5 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Paired Box 5
Gene Summary 1 This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Chromosome 1 Chromosome 9
Locus 1 9p13.2
Coordinates 1 This gene maps to 36838530-37034476 in GRCh37 coordinates.
Associated Diseases Sarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PPP2R4/PAX5-09267-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PPP2R4/PAX5-09267-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PPP2R4/PAX5-09267-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PPP2R4/PAX5-09267-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PPP2R4/PAX5-09267-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PPP2R4/PAX5-09267-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PPP2R4/PAX5-09267-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PPP2R4/PAX5-09267-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PPP2R4/PAX5-09267-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PPP2R4/PAX5-09267-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PPP2R4/PAX5-09267-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PPP2R4/PAX5-09267-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PPP2R4/PAX5-09267-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PPP2R4/PAX5-09267-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PPP2R4/PAX5-09267-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PPP2R4/PAX5-09267-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PPP2R4/PAX5-09267-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PPP2R4/PAX5-09267-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PPP2R4/PAX5-09267-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PPP2R4/PAX5-09267-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PPP2R4/PAX5-09267-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PPP2R4/PAX5-09267-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PPP2R4/PAX5-09267-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PPP2R4/PAX5-09267-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PPP2R4/PAX5-09267-AQAQ 467nm;467nm 418nm;418nm

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