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PPP1R10-MUS81 Gene Fusion FISH Probe

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Catalog: GFFP-PPP1R10/MUS81-09312
Classification: Gene Fusion FISH Probes
Description: The PPP1R10-MUS81 Gene Fusion FISH Probecan detect the fusion of PPP1R10 and MUS81 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PPP1R10-MUS81 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Protein Phosphatase 1 Regulatory Subunit 10
Gene Summary 1 This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Chromosome 1 Chromosome 6_mcf_hap5
Locus 1 6p21.33
Coordinates 1 This gene maps to 1950036-1966876 in GRCh37 coordinates.
Gene Name 2 MUS81 Structure-specific Endonuclease Subunit
Gene Summary 2 This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks. [provided by RefSeq, Jun 2017]
Chromosome 2 Chromosome11
Locus 2 11q13.1
Coordinates 2 This gene maps to 65627871-65633914 in GRCh37 coordinates.
Associated Diseases Skin Cutaneous Melanoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PPP1R10/MUS81-09312-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PPP1R10/MUS81-09312-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PPP1R10/MUS81-09312-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PPP1R10/MUS81-09312-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PPP1R10/MUS81-09312-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PPP1R10/MUS81-09312-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PPP1R10/MUS81-09312-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PPP1R10/MUS81-09312-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PPP1R10/MUS81-09312-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PPP1R10/MUS81-09312-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PPP1R10/MUS81-09312-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PPP1R10/MUS81-09312-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PPP1R10/MUS81-09312-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PPP1R10/MUS81-09312-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PPP1R10/MUS81-09312-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PPP1R10/MUS81-09312-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PPP1R10/MUS81-09312-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PPP1R10/MUS81-09312-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PPP1R10/MUS81-09312-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PPP1R10/MUS81-09312-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PPP1R10/MUS81-09312-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PPP1R10/MUS81-09312-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PPP1R10/MUS81-09312-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PPP1R10/MUS81-09312-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PPP1R10/MUS81-09312-AQAQ 467nm;467nm 418nm;418nm

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