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PLA2G2A-MBTPS1 Gene Fusion FISH Probe

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Catalog: GFFP-PLA2G2A/MBTPS1-08845
Classification: Gene Fusion FISH Probes
Description: The PLA2G2A-MBTPS1 Gene Fusion FISH Probecan detect the fusion of PLA2G2A and MBTPS1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PLA2G2A-MBTPS1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Phospholipase A2 Group IIA
Gene Summary 1 The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]
Chromosome 1 Chromosome 1
Locus 1 1p36.13
Coordinates 1 This gene maps to 20301923-20306932 in GRCh37 coordinates.
Gene Name 2 Membrane Bound Transcription Factor Peptidase, Site 1
Gene Summary 2 This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]
Chromosome 2 Chromosome16
Locus 2 16q23.3-q24.1
Coordinates 2 This gene maps to 84087368-84150517 in GRCh37 coordinates.
Associated Diseases Prostate Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PLA2G2A/MBTPS1-08845-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PLA2G2A/MBTPS1-08845-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PLA2G2A/MBTPS1-08845-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PLA2G2A/MBTPS1-08845-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PLA2G2A/MBTPS1-08845-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PLA2G2A/MBTPS1-08845-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PLA2G2A/MBTPS1-08845-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PLA2G2A/MBTPS1-08845-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PLA2G2A/MBTPS1-08845-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PLA2G2A/MBTPS1-08845-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PLA2G2A/MBTPS1-08845-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PLA2G2A/MBTPS1-08845-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PLA2G2A/MBTPS1-08845-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PLA2G2A/MBTPS1-08845-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PLA2G2A/MBTPS1-08845-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PLA2G2A/MBTPS1-08845-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PLA2G2A/MBTPS1-08845-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PLA2G2A/MBTPS1-08845-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PLA2G2A/MBTPS1-08845-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PLA2G2A/MBTPS1-08845-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PLA2G2A/MBTPS1-08845-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PLA2G2A/MBTPS1-08845-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PLA2G2A/MBTPS1-08845-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PLA2G2A/MBTPS1-08845-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PLA2G2A/MBTPS1-08845-AQAQ 467nm;467nm 418nm;418nm

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