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PDE1A-PPP1R1C Gene Fusion FISH Probe

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Catalog: GFFP-PDE1A/PPP1R1C-08597
Classification: Gene Fusion FISH Probes
Description: The PDE1A-PPP1R1C Gene Fusion FISH Probecan detect the fusion of PDE1A and PPP1R1C genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PDE1A-PPP1R1C Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Phosphodiesterase 1A
Gene Summary 1 Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009]
Chromosome 1 Chromosome 2
Locus 1 2q32.1
Coordinates 1 This gene maps to 183007182-183387253 in GRCh37 coordinates.
Gene Name 2 Protein Phosphatase 1 Regulatory Inhibitor Subunit 1C
Gene Summary 2 Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010]
Chromosome 2 Chromosome2
Locus 2 2q31.3-q32.1
Coordinates 2 This gene maps to 182850550-182982419 in GRCh37 coordinates.
Associated Diseases Kidney Renal Clear Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PDE1A/PPP1R1C-08597-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PDE1A/PPP1R1C-08597-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PDE1A/PPP1R1C-08597-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PDE1A/PPP1R1C-08597-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PDE1A/PPP1R1C-08597-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PDE1A/PPP1R1C-08597-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PDE1A/PPP1R1C-08597-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PDE1A/PPP1R1C-08597-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PDE1A/PPP1R1C-08597-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PDE1A/PPP1R1C-08597-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PDE1A/PPP1R1C-08597-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PDE1A/PPP1R1C-08597-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PDE1A/PPP1R1C-08597-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PDE1A/PPP1R1C-08597-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PDE1A/PPP1R1C-08597-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PDE1A/PPP1R1C-08597-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PDE1A/PPP1R1C-08597-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PDE1A/PPP1R1C-08597-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PDE1A/PPP1R1C-08597-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PDE1A/PPP1R1C-08597-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PDE1A/PPP1R1C-08597-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PDE1A/PPP1R1C-08597-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PDE1A/PPP1R1C-08597-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PDE1A/PPP1R1C-08597-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PDE1A/PPP1R1C-08597-AQAQ 467nm;467nm 418nm;418nm

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