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NUP88-NLRP1 Gene Fusion FISH Probe

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Catalog: GFFP-NUP88/NLRP1-08300
Classification: Gene Fusion FISH Probes
Description: The NUP88-NLRP1 Gene Fusion FISH Probecan detect the fusion of NUP88 and NLRP1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NUP88-NLRP1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Nucleoporin 88
Gene Summary 1 The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Chromosome 1 Chromosome 17
Locus 1 17p13.2
Coordinates 1 This gene maps to 5289345-5323059 in GRCh37 coordinates.
Gene Name 2 NLR Family Pyrin Domain Containing 1
Gene Summary 2 This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome17
Locus 2 17p13.2
Coordinates 2 This gene maps to 5404718-5487832 in GRCh37 coordinates.
Associated Diseases Bladder Urothelial Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NUP88/NLRP1-08300-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NUP88/NLRP1-08300-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NUP88/NLRP1-08300-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NUP88/NLRP1-08300-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NUP88/NLRP1-08300-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NUP88/NLRP1-08300-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NUP88/NLRP1-08300-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NUP88/NLRP1-08300-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NUP88/NLRP1-08300-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NUP88/NLRP1-08300-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NUP88/NLRP1-08300-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NUP88/NLRP1-08300-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NUP88/NLRP1-08300-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NUP88/NLRP1-08300-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NUP88/NLRP1-08300-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NUP88/NLRP1-08300-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NUP88/NLRP1-08300-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NUP88/NLRP1-08300-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NUP88/NLRP1-08300-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NUP88/NLRP1-08300-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NUP88/NLRP1-08300-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NUP88/NLRP1-08300-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NUP88/NLRP1-08300-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NUP88/NLRP1-08300-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NUP88/NLRP1-08300-AQAQ 467nm;467nm 418nm;418nm

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