NUB1-ABCB8 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-NUB1/ABCB8-08051 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NUB1-ABCB8 Gene Fusion FISH Probecan detect the fusion of NUB1 and ABCB8 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NUB1-ABCB8 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
ATP Binding Cassette Subfamily B Member 8 |
Gene Summary 1 |
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
Chromosome 1 |
Chromosome 7 |
Locus 1 |
7q36.1 |
Coordinates 1 |
This gene maps to 150725509-150744869 in GRCh37 coordinates. |
Gene Name 2 |
Negative Regulator Of Ubiquitin Like Proteins 1 |
Gene Summary 2 |
This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
Chromosome 2 |
Chromosome7 |
Locus 2 |
7q36.1 |
Coordinates 2 |
This gene maps to 151038846-151075548 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NUB1/ABCB8-08051-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NUB1/ABCB8-08051-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NUB1/ABCB8-08051-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NUB1/ABCB8-08051-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NUB1/ABCB8-08051-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NUB1/ABCB8-08051-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NUB1/ABCB8-08051-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NUB1/ABCB8-08051-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NUB1/ABCB8-08051-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NUB1/ABCB8-08051-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NUB1/ABCB8-08051-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NUB1/ABCB8-08051-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NUB1/ABCB8-08051-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NUB1/ABCB8-08051-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NUB1/ABCB8-08051-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NUB1/ABCB8-08051-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NUB1/ABCB8-08051-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NUB1/ABCB8-08051-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NUB1/ABCB8-08051-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NUB1/ABCB8-08051-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NUB1/ABCB8-08051-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NUB1/ABCB8-08051-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NUB1/ABCB8-08051-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NUB1/ABCB8-08051-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NUB1/ABCB8-08051-AQAQ |
467nm;467nm |
418nm;418nm |
|
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