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NR3C1-HMHB1 Gene Fusion FISH Probe

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Catalog: GFFP-NR3C1/HMHB1-08131
Classification: Gene Fusion FISH Probes
Description: The NR3C1-HMHB1 Gene Fusion FISH Probecan detect the fusion of NR3C1 and HMHB1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NR3C1-HMHB1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Nuclear Receptor Subfamily 3 Group C Member 1
Gene Summary 1 This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
Chromosome 1 Chromosome 5
Locus 1 5q31.3
Coordinates 1 This gene maps to 142657495-142815077 in GRCh37 coordinates.
Gene Name 2 Histocompatibility Minor HB-1
Gene Summary 2 This gene encodes one of the minor histocompatibility antigens, which play an important role in the induction of cytotoxic T lymphocyte (CTL) reactivity against leukemia after human histocompatibility leukocyte antigen (HLA)-identical allogeneic bone marrow transplantation (BMT). This gene is only expressed in B cell acute lymphoblastic leukemia cells and Epstein-Barr virus-transformed B cells. The translation of this mRNA initiates at a non-AUG (CUG) codon. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome5
Locus 2 5q31.3
Coordinates 2 This gene maps to 143191725-143200284 in GRCh37 coordinates.
Associated Diseases Glioblastoma Multiforme
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NR3C1/HMHB1-08131-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NR3C1/HMHB1-08131-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NR3C1/HMHB1-08131-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NR3C1/HMHB1-08131-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NR3C1/HMHB1-08131-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NR3C1/HMHB1-08131-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NR3C1/HMHB1-08131-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NR3C1/HMHB1-08131-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NR3C1/HMHB1-08131-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NR3C1/HMHB1-08131-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NR3C1/HMHB1-08131-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NR3C1/HMHB1-08131-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NR3C1/HMHB1-08131-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NR3C1/HMHB1-08131-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NR3C1/HMHB1-08131-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NR3C1/HMHB1-08131-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NR3C1/HMHB1-08131-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NR3C1/HMHB1-08131-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NR3C1/HMHB1-08131-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NR3C1/HMHB1-08131-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NR3C1/HMHB1-08131-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NR3C1/HMHB1-08131-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NR3C1/HMHB1-08131-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NR3C1/HMHB1-08131-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NR3C1/HMHB1-08131-AQAQ 467nm;467nm 418nm;418nm

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