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NR2C1-BCL7A Gene Fusion FISH Probe

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Catalog: GFFP-NR2C1/BCL7A-08137
Classification: Gene Fusion FISH Probes
Description: The NR2C1-BCL7A Gene Fusion FISH Probecan detect the fusion of NR2C1 and BCL7A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NR2C1-BCL7A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 BCL Tumor Suppressor 7A
Gene Summary 1 This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 12
Locus 1 12q24.31
Coordinates 1 This gene maps to 122459860-122499950 in GRCh37 coordinates.
Gene Name 2 Nuclear Receptor Subfamily 2 Group C Member 1
Gene Summary 2 This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome12
Locus 2 12q22
Coordinates 2 This gene maps to 95414057-95467404 in GRCh37 coordinates.
Associated Diseases Sarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NR2C1/BCL7A-08137-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NR2C1/BCL7A-08137-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NR2C1/BCL7A-08137-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NR2C1/BCL7A-08137-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NR2C1/BCL7A-08137-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NR2C1/BCL7A-08137-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NR2C1/BCL7A-08137-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NR2C1/BCL7A-08137-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NR2C1/BCL7A-08137-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NR2C1/BCL7A-08137-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NR2C1/BCL7A-08137-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NR2C1/BCL7A-08137-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NR2C1/BCL7A-08137-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NR2C1/BCL7A-08137-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NR2C1/BCL7A-08137-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NR2C1/BCL7A-08137-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NR2C1/BCL7A-08137-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NR2C1/BCL7A-08137-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NR2C1/BCL7A-08137-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NR2C1/BCL7A-08137-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NR2C1/BCL7A-08137-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NR2C1/BCL7A-08137-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NR2C1/BCL7A-08137-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NR2C1/BCL7A-08137-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NR2C1/BCL7A-08137-AQAQ 467nm;467nm 418nm;418nm

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