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NMNAT2-ATF6 Gene Fusion FISH Probe

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Catalog: GFFP-NMNAT2/ATF6-07853
Classification: Gene Fusion FISH Probes
Description: The NMNAT2-ATF6 Gene Fusion FISH Probecan detect the fusion of NMNAT2 and ATF6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NMNAT2-ATF6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Activating Transcription Factor 6
Gene Summary 1 This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011]
Chromosome 1 Chromosome 1
Locus 1 1q23.3
Coordinates 1 This gene maps to 161736033-161933860 in GRCh37 coordinates.
Gene Name 2 Nicotinamide Nucleotide Adenylyltransferase 2
Gene Summary 2 This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome1
Locus 2 1q25.3
Coordinates 2 This gene maps to 183217371-183387634 in GRCh37 coordinates.
Associated Diseases Brain Lower Grade Glioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NMNAT2/ATF6-07853-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NMNAT2/ATF6-07853-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NMNAT2/ATF6-07853-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NMNAT2/ATF6-07853-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NMNAT2/ATF6-07853-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NMNAT2/ATF6-07853-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NMNAT2/ATF6-07853-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NMNAT2/ATF6-07853-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NMNAT2/ATF6-07853-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NMNAT2/ATF6-07853-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NMNAT2/ATF6-07853-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NMNAT2/ATF6-07853-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NMNAT2/ATF6-07853-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NMNAT2/ATF6-07853-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NMNAT2/ATF6-07853-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NMNAT2/ATF6-07853-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NMNAT2/ATF6-07853-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NMNAT2/ATF6-07853-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NMNAT2/ATF6-07853-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NMNAT2/ATF6-07853-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NMNAT2/ATF6-07853-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NMNAT2/ATF6-07853-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NMNAT2/ATF6-07853-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NMNAT2/ATF6-07853-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NMNAT2/ATF6-07853-AQAQ 467nm;467nm 418nm;418nm

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