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NIPBL-MAPRE1 Gene Fusion FISH Probe

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Catalog: GFFP-NIPBL/MAPRE1-07903
Classification: Gene Fusion FISH Probes
Description: The NIPBL-MAPRE1 Gene Fusion FISH Probecan detect the fusion of NIPBL and MAPRE1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NIPBL-MAPRE1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Microtubule Associated Protein RP/EB Family Member 1
Gene Summary 1 The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 20
Locus 1 20q11.21
Coordinates 1 This gene maps to 31407698-31438211 in GRCh37 coordinates.
Gene Name 2 NIPBL, Cohesin Loading Factor
Gene Summary 2 This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome5
Locus 2 5p13.2
Coordinates 2 This gene maps to 36876860-37065921 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NIPBL/MAPRE1-07903-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NIPBL/MAPRE1-07903-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NIPBL/MAPRE1-07903-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NIPBL/MAPRE1-07903-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NIPBL/MAPRE1-07903-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NIPBL/MAPRE1-07903-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NIPBL/MAPRE1-07903-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NIPBL/MAPRE1-07903-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NIPBL/MAPRE1-07903-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NIPBL/MAPRE1-07903-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NIPBL/MAPRE1-07903-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NIPBL/MAPRE1-07903-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NIPBL/MAPRE1-07903-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NIPBL/MAPRE1-07903-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NIPBL/MAPRE1-07903-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NIPBL/MAPRE1-07903-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NIPBL/MAPRE1-07903-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NIPBL/MAPRE1-07903-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NIPBL/MAPRE1-07903-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NIPBL/MAPRE1-07903-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NIPBL/MAPRE1-07903-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NIPBL/MAPRE1-07903-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NIPBL/MAPRE1-07903-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NIPBL/MAPRE1-07903-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NIPBL/MAPRE1-07903-AQAQ 467nm;467nm 418nm;418nm

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