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MTHFS-BCL2A1 Gene Fusion FISH Probe

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Catalog: GFFP-MTHFS/BCL2A1-15333
Classification: Gene Fusion FISH Probes
Description: The MTHFS-BCL2A1 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MTHFS-BCL2A1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 BCL2 Related Protein A1
Gene Summary 1 This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 15
Locus 1 15q25.1
Coordinates 1 This gene maps to 80253231-80263643in GRCh37 coordinates.
Gene Name 2 Methenyltetrahydrofolate Synthetase
Gene Summary 2 The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Chromosome 2 Chromosome15
Locus 2 15q25.1
Coordinates 2 This gene maps to 80135888-80189627 in GRCh37 coordinates.
Associated Diseases Liver Hepatocellular Carcinoma; Kidney Renal Clear Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MTHFS/BCL2A1-15333-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MTHFS/BCL2A1-15333-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MTHFS/BCL2A1-15333-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MTHFS/BCL2A1-15333-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MTHFS/BCL2A1-15333-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MTHFS/BCL2A1-15333-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MTHFS/BCL2A1-15333-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MTHFS/BCL2A1-15333-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MTHFS/BCL2A1-15333-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MTHFS/BCL2A1-15333-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MTHFS/BCL2A1-15333-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MTHFS/BCL2A1-15333-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MTHFS/BCL2A1-15333-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MTHFS/BCL2A1-15333-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MTHFS/BCL2A1-15333-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MTHFS/BCL2A1-15333-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MTHFS/BCL2A1-15333-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MTHFS/BCL2A1-15333-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MTHFS/BCL2A1-15333-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MTHFS/BCL2A1-15333-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MTHFS/BCL2A1-15333-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MTHFS/BCL2A1-15333-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MTHFS/BCL2A1-15333-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MTHFS/BCL2A1-15333-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MTHFS/BCL2A1-15333-AQAQ 467nm;467nm 418nm;418nm

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