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MTCH2-FHIT Gene Fusion FISH Probe

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Catalog: GFFP-MTCH2/FHIT-07437
Classification: Gene Fusion FISH Probes
Description: The MTCH2-FHIT Gene Fusion FISH Probecan detect the fusion of MTCH2 and FHIT genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MTCH2-FHIT Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Fragile Histidine Triad
Gene Summary 1 The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]
Chromosome 1 Chromosome 3
Locus 1 3p14.2
Coordinates 1 This gene maps to 59735035-61237133 in GRCh37 coordinates.
Gene Name 2 Mitochondrial Carrier 2
Gene Summary 2 This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons. [provided by RefSeq, Dec 2017]
Chromosome 2 Chromosome11
Locus 2 11p11.2
Coordinates 2 This gene maps to 47638857-47664206 in GRCh37 coordinates.
Associated Diseases Ovarian Serous Cystadenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MTCH2/FHIT-07437-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MTCH2/FHIT-07437-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MTCH2/FHIT-07437-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MTCH2/FHIT-07437-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MTCH2/FHIT-07437-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MTCH2/FHIT-07437-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MTCH2/FHIT-07437-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MTCH2/FHIT-07437-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MTCH2/FHIT-07437-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MTCH2/FHIT-07437-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MTCH2/FHIT-07437-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MTCH2/FHIT-07437-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MTCH2/FHIT-07437-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MTCH2/FHIT-07437-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MTCH2/FHIT-07437-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MTCH2/FHIT-07437-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MTCH2/FHIT-07437-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MTCH2/FHIT-07437-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MTCH2/FHIT-07437-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MTCH2/FHIT-07437-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MTCH2/FHIT-07437-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MTCH2/FHIT-07437-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MTCH2/FHIT-07437-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MTCH2/FHIT-07437-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MTCH2/FHIT-07437-AQAQ 467nm;467nm 418nm;418nm

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