MMP15-CDH5 Gene Fusion FISH Probe
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Catalog: |
GFFP-MMP15/CDH5-07224 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MMP15-CDH5 Gene Fusion FISH Probecan detect the fusion of MMP15 and CDH5 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MMP15-CDH5 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Cadherin 5 |
Gene Summary 1 |
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015] |
Chromosome 1 |
Chromosome 16 |
Locus 1 |
16q21 |
Coordinates 1 |
This gene maps to 66400524-66438689 in GRCh37 coordinates. |
Gene Name 2 |
Matrix Metallopeptidase 15 |
Gene Summary 2 |
This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016] |
Chromosome 2 |
Chromosome16 |
Locus 2 |
16q21 |
Coordinates 2 |
This gene maps to 58059281-58080804 in GRCh37 coordinates. |
Associated Diseases |
Bladder Urothelial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MMP15/CDH5-07224-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MMP15/CDH5-07224-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MMP15/CDH5-07224-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MMP15/CDH5-07224-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MMP15/CDH5-07224-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MMP15/CDH5-07224-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MMP15/CDH5-07224-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MMP15/CDH5-07224-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MMP15/CDH5-07224-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MMP15/CDH5-07224-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MMP15/CDH5-07224-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MMP15/CDH5-07224-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MMP15/CDH5-07224-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MMP15/CDH5-07224-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MMP15/CDH5-07224-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MMP15/CDH5-07224-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MMP15/CDH5-07224-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MMP15/CDH5-07224-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MMP15/CDH5-07224-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MMP15/CDH5-07224-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MMP15/CDH5-07224-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MMP15/CDH5-07224-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MMP15/CDH5-07224-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MMP15/CDH5-07224-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MMP15/CDH5-07224-AQAQ |
467nm;467nm |
418nm;418nm |
|
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